Ghetsis/Anime/Main

Ghetsis is the head of Team Plasma, and the main antagonist of the ''Best Wishes! Season 2: Episode N arc. He debuted in Team Plasma's Pokémon Power Plot!'', where he was seen briefly contacting Colress via a hologram communicator. He and Colress discussed the current status of the Pokémon control experiment, and when, , and Looker approached Team Plasma's laboratory, Ghetsis ordered Colress to turn the experimental Pokémon loose on them.

He appeared again, this time in person, in Team Plasma's Pokémon Manipulation!. He was seen contacting Colress for an update on his Pokémon control experiment. Later, Ghetsis spoke to several s, who were spying on the excavations made at the as well as looking for  and conducting the mysterious "Project G" and "Project F".

In Secrets From Out of the Fog!, Ghetsis was seen discussing his plans with Colress and Aldith. He was also seen in flashbacks to N's past, in which he raised N alongside Anthea and Concordia and wild Pokémon. In a later flashback, a ceremony he led in N's Castle involving N and the Seven Sages was interrupted by, infuriating him.

He briefly appeared in Meowth, Colress and Team Rivalry!, where he met with Colress, Aldith and Barret via hologram and revealing the existence of the Light Stone to them.

He briefly appeared via a communicator Ash and N: A Clash of Ideals! before arriving at the White Ruins in Team Plasma and the Awakening Ceremony!. With his followers having subdued Team Plasma's enemies, Ghetsis took the Light Stone and placed it on a pedestal in the ruins, then used his staff to initiate the ritual leading to Reshiram's awakening.

In What Lies Beyond Truth and Ideals!, Ghetsis successfully summoned Reshiram and, with the help of Colress's machine, took control of it. Despite turning it on his enemies, however, he lost control of Reshiram when Colress's machine was destroyed. Ultimately, he was arrested by Looker along with the rest of his followers.