Kanto Route 22/Route description

After departing Viridian City, Route 22 turns south at a line of trees before circling around the bottom of the treeline and passing north through a grassy patch of wild Pokémon. North of the patch, the route turns west, passing over a small hill as well as a small pond. Route 22 then turns south, hopping over a ledge into another patch of grass. Six paces to the south, Route 22 returns west, then north, passing through a hole in the fence outside the checkpoint building. To the northeast, the road goes through a break in a ledge before entering the building, emerging as on the north side.

The ledge over the western grass patch causes the route path from Viridian to the Pokémon League building to become a westbound-only path. To return east, a ledge lines the bottom of the route, providing a pathway for Trainers to return to Viridian. The pathway, two paces wide, rejoins the route southwest of Viridian.

makes two appearances on Route 22 near the first grass patch in Generations and. The first battle is optional; in, it affects what Pokémon become part of his team later in the game. The second battle is mandatory.

In, the player can witness Giovanni abandoning here during the  event, presumably heading to Tohjo Falls.