Serena (anime)/Anime/History/Pre-series

As a young child, Serena was sent to Kanto, against her will, to attend a Pokémon Summer Camp, which was hosted by. One day, while at the camp, she got lost in a nearby forest and was startled by a, falling over and hurting her knee. Then, she met Ash Ketchum, who was looking for the same Poliwag and spotted Serena. Noticing her knee injury, he pulled out a handkerchief and wrapped it around her wounded knee, saying that it is a good-luck charm and that the pain would go away. However, when Serena's knee continued to hurt, Ash told her "Don't give up till it's over" and helped her up before escorting her out of the forest. Afterwards, she returned to Kalos, bringing along the handkerchief and the memory of her meeting with Ash.